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TNIK (Ser764) Antibody, Cy5.5 Conjugated

TNIK (Ser764) Antibody, Cy5.5 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, TNIK (Ser764) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTNIK Ser764
Specificity Phosphorylation site corresponds to Ser735 in mouse, This is a highly specific antibody against TNIK Ser764
ModificationPhosphorylation
Modification siteSer764
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range759-766/1360
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764
Gene ID number23043
Swiss ProtQ9UKE5
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Appears to act upstream of the JUN N-terminal pathway, May act by phosphorylating TCF4/TCF7L2, May play a role in the response to environmental stress, More generally, Part of a signaling complex composed of NEDD4, Phosphorylates SMAD1 on Thr-322, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development, Recruited to promoters of Wnt target genes and required to activate their expression, it may play a role in cytoskeletal rearrangements and regulate cell spreading, Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms KIAA0551
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetTNIK (Ser764) Conjugated
Short name Conjugated, TNIK (Ser764) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, TRAF2 and NCK interacting kinase (Ser764) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627, TNIK and IDBG-64741 and ENSG00000154310 and 23043, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007256 and activation of JNKK activity and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005083: small GTPase regulator activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005083: small GTPase regulator activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048814 and regulation of dendrite morphogenesis and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, TRAF2 and NCK interacting kinase
Identity 30765
Gene TNIK
Long gene name TRAF2 and NCK interacting kinase
Locus 3q26, 2-q26, 31
Discovery year 2004-02-26
GenBank acession AF172264
Entrez gene record 23043
Pubmed identfication 9628581 10521462
RefSeq identity XM_039796
Havana BLAST/BLAT OTTHUMG00000159036

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