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TPOR Antibody, ALEXA FLUOR 488

TPOR Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, TPOR Polyclonal Antibody
Also known asAnti-TPOR PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTPOR
SpecificityThis is a highly specific antibody against TPOR
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TPOR
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Expression of c-Mpl is restricted to hematopoietic tissues and cells, Muta-tions in c-Mpl have been implicated as the cause of certain human disorders, Stimulation of c-Mpl with TPO results in the activation of the Janus tyrosine kinase family members, TPO exerts its biological effects through the TPO receptor, Tyk 2 and JAK2, also known as c-Mpl ligand (c-Mpl L), c-Mpl, c-Mpl is a member of the cytokine receptor superfamily, causing their nuclear translocation and the transcription of Stat responsive genes, fetal liver and CD34+ cells, including congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia with absent radii (TAR) syndrome, is a cytokine that plays a central role in megakaryopoiesis by influencing the development and maturation of megakaryocytes and platelet production from hematopoietic stem cells, spleen, such as bone marrow, which in turn phosphorylate Stat5 and Stat3, Thrombopoietin (TPO or THPO)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms CD110 TPOR
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TPOR Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetTPOR
Short nameTPOR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, TPOR (Antibody to)
Alternative techniqueantibodies
Identity 7217
Gene MPL
Long gene name MPL proto-oncogene, thrombopoietin receptor
Synonyms gene name myeloproliferative leukemia virus oncogene
Locus 1p34, 2
Discovery year 1990-09-10
GenBank acession M90102
Entrez gene record 4352
Pubmed identfication 1608974
RefSeq identity NM_005373
Classification CD molecules Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000007429
Locus Specific Databases LRG_510

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