Name : TREM2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6668080043
| Long name | TREM2 Primary Polyclonal Antibody |
| Also known as | TREM2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | TREM2 |
| Specificity | This is a highly specific antibody against TREM2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 20-70/230 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TREM2 |
| Gene ID number | 54209 |
| Swiss Prot | Q9NZC2 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells, May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | TREM2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2, TREM-2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TREM2 |
| Short name | TREM2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | triggering receptor expressed on myeloid cells 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, TREM2 and IDBG-630863 and ENSBTAG00000007275 and 506467, TREM2 and IDBG-86566 and ENSG00000095970 and 54209, Trem2 and IDBG-189871 and ENSMUSG00000023992 and 83433, scaffold protein binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0002588 and positive regulation of antigen processing and presentation of peptide antigen via MHC class II and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006959 and humoral immune response and biological process this GO :0007411 and axon guidance and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045087 and innate immune response and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0097028 and dendritic cell differentiation and biological process this GO :0097110 and scaffold protein binding and molecular function this GO :1903078 and positive regulation of protein localization to plasma membrane and biological process this GO :1903082 and positive regulation of C-C chemokine receptor CCR7 signaling pathway and biological process this GO :2000350 and positive regulation of CD40 signaling pathway and biological process, this GO :0001530: lipopolysaccharide binding, this GO :0001530: lipopolysaccharide binding and also this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0097110: scaffold protein binding, this GO :0004872: receptor activity, this GO :0005515: protein binding, this GO :0097110: scaffold protein binding, triggering receptor expressed on myeloid cells 2 |
| Identity | 17761 |
| Gene | TREM2 |
| Long gene name | triggering receptor expressed on myeloid cells 2 |
| Synonyms gene name | triggering receptor expressed on myeloid cells 2a |
| Synonyms | TREM-2 Trem2a Trem2b Trem2c |
| Locus | 6p21, 1 |
| Discovery year | 2002-08-09 |
| GenBank acession | AF213457 |
| Entrez gene record | 54209 |
| Pubmed identfication | 10799849 12080485 |
| RefSeq identity | NM_018965 |
| Classification | V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000014671 |
| Locus Specific Databases | LRG_631 |