TREML2 Antibody

TREML2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	TREML2 Primary Polyclonal Antibody
Also known as	TREML2 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	TREML2
Specificity	This is a highly specific antibody against TREML2
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Subcellular location	Extracellular
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TREML2
Gene ID number	79865
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	It is a cell surface receptor that may play a role in the innate and adaptive immune response, Monocytes in the bone marrow or peripheral blood do not express detectable levels of TREML2, TREML2 does not exhibit any of the features associated with classical tyrosine-based signaling, TREML2 is expressed on B lineage cells early in development, TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 and TREM2, TREML2 is present on neutrophils in the bone marrow as well as the periphery, TREML2 is unique in that it lacks either the conserved transmembrane lysine residue or ITAM/ITIMs within its own cytoplasmic domain, Thus, and inflammatory stimuli result in a dramatic increase in the expression of TREML2 on these cells in vivo, and it contains 1 Ig-like V-type (immunoglobulin-like) domain, and the highest level of expression is detected on those mature peripheral B cell subpopulations that are involved in the initial humoral immune response against bacterial pathogens, but it has distinct structural and functional properties, but its expression is up-regulated in conjunction with differentiation into macrophages, TREML2 is a single-pass type I membrane protein, TREML2 is expressed throughout B cell development in addition to being expressed on macrophages and neutrophils and is the only TREM molecule to be found on lymphocytes
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	Chromosome 6 open reading frame 76, FLJ13693, MGC149715, MGC149716, TLT 2, TLT2, TREM like transcript 2, TRML2_HUMAN, Trem like transcript 2 protein, Triggering receptor expressed on myeloid cells like 2, Triggering receptor expressed on myeloid cells like protein 2, C6orf76
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	TREML2
Short name	TREML2 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	triggering receptor expressed on myeloid cells-like 2 (Antibody to)
Alternative technique	antibodies
Alternative to gene target	Cell surfaces, TREML2 and IDBG-630865 and ENSBTAG00000015707 and 515548, TREML2 and IDBG-86610 and ENSG00000112195 and 79865, Treml2 and IDBG-189835 and ENSMUSG00000071068 and 328833, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0042110 and T cell activation and biological process this GO :0045087 and innate immune response and biological process, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, triggering receptor expressed on myeloid cells-like 2
Identity	21092
Gene	TREML2
Long gene name	triggering receptor expressed on myeloid cells like 2
Synonyms gene	C6orf76
Synonyms gene name	chromosome 6 open reading frame 76 triggering receptor expressed on myeloid cells-like 2
Synonyms	FLJ13693 TLT2 dJ238O23, 1
Synonyms name	TREM-like transcript 2
Locus	6p21, 1
Discovery year	2003-05-19
GenBank acession	AK023755
Entrez gene record	79865
Pubmed identfication	12645956
RefSeq identity	NM_024807
Classification	V-set domain containing
Havana BLAST/BLAT	OTTHUMG00000016349

TREML2 Antibody

TREML2 Antibody size: 0.1ml 263

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