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Tuberin Antibody, ALEXA FLUOR 488

Tuberin Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Tuberin Polyclonal Antibody
Also known asAnti-Tuberin PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTuberin
SpecificityThis is a highly specific antibody against Tuberin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1600-1650/1809
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tuberin
Gene ID Number7249
Swiss ProtP49815
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, Implicated as a tumor suppressor, Involved in microtubule-mediated protein transport, Mutations in TSC2 lead to constitutive activation of RAP1A in tumors, Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro, a direct activator of the protein kinase activity of mTORC1, but this seems to be due to unregulated mTOR signaling, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling, In complex with TSC1
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms tuberin LAM PPP1R160 TSC2
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Tuberin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetTuberin
Short nameTuberin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Tuberin (Antibody to)
Alternative techniqueantibodies
Identity 12365
Gene TSC4
Long gene name tuberous sclerosis 2
Synonyms name protein phosphatase 1, regulatory subunit 160
Locus 16p13, 3
Discovery year 1989-05-25
GenBank acession AB014460
Entrez gene record 7249
Pubmed identfication 1303246 7558029
RefSeq identity NM_000548
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000128745
Locus Specific Databases TSC2 Mutation Database Tuberous sclerosis database LRG_487

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