Name : TUSC2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7366956161
| Long name | TUSC2 Primary Polyclonal Antibody |
| Also known as | TUSC2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | TUSC2 |
| Specificity | This is a highly specific antibody against TUSC2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TUSC2 |
| Gene ID number | 11334 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | AKT, Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions, PDGFR, Restoration of TUSC2 function in 3p21, TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, and c-Kit, c-Abl, 3 region where allele losses and genetic alterations occur early and frequently for many human cancers, 3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics, TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FUS1, Fusion 1 protein, PAP, PDAP2, PDGFA associated protein 2, TUSC 2, TUSC2_HUMAN, Tumor suppressor candidate 2, C3orf11 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TUSC2 |
| Short name | TUSC2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | TUSC2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17034 |
| Gene | TUSC2 |
| Long gene name | tumor suppressor candidate 2 |
| Synonyms gene | PDAP2 |
| Synonyms gene name | PDGFA associated protein 2 |
| Synonyms | FUS1 PAP C3orf11 |
| Locus | 3p21, 31 |
| Discovery year | 2003-09-25 |
| GenBank acession | AF055479 |
| Entrez gene record | 11334 |
| Pubmed identfication | 8780057 11593436 |
| RefSeq identity | NM_007275 |
| Havana BLAST/BLAT | OTTHUMG00000156877 |