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UBE2O Antibody, FITC Conjugated

UBE2O Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, UBE2O Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUBE2O
SpecificityThis is a highly specific antibody against UBE2O
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human UBE2O/E2 230K
Gene ID number63893
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Rat, Mouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BRCA1 is directly involved in DNA repair, Expressed predominately in heart and skeletal muscle, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene encoding UBE2O maps to human chromosome 17, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, UBE2O functions to catalyze the ATP-dependent covalent attachment of ubiquitin to select proteins, also known as E2-230K, colon, is a 1, namely, p53 and BRCA1, prostate gland and fallopian tubes, thereby targeting the ubiquitinated proteins for proteasomal degradation, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, which comprises over 2, 200 genes, 292 amino acid member of the uniquitin-conjugating enzyme family that is involved in protein modification, 5% of the human genome and encodes over 1, UBE20
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms E2-230K
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetUBE2O Conjugated
Short name FITC Conjugated, UBE2O Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, UBE2O (Antibody to)
Alternative techniqueantibodies
Identity 29554
Gene UBE2O
Long gene name ubiquitin conjugating enzyme E2 O
Synonyms gene name ubiquitin-conjugating enzyme E2O
Locus 17q25, 1
Discovery year 2005-12-15
GenBank acession AB051521
Entrez gene record 63893
Pubmed identfication 11311559 11214970
RefSeq identity NM_022066
Havana BLAST/BLAT OTTHUMG00000180178

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