Name : Ubiquitin D Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN2787576720
| Long name | FITC Conjugated, Ubiquitin D Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Ubiquitin D |
| Specificity | This is a highly specific antibody against Ubiquitin D |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 60-100/165 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human Ubiquitin D |
| Gene ID number | 10537 |
| Swiss Prot | O15205 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Conjugation ability activated by UBA6, May be involved in dendritic cell (DC) maturation, May be involved in the formation of aggresomes when proteasome is saturated or impaired, Mediates apoptosis in a caspase-dependent manner, Mediates mitotic non-disjunction and chromosome instability, Probably functions as a survival factor, Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2), Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha, Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs), by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN), in a NUB1L-dependent manner, in long-term in vitro culture and cancers, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses, Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | Diubiquitin, GABBR1, UBD, UBD-3, Ubiquitin D, Ubiquitin-like protein FAT10, FAT10 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Ubiquitin D Conjugated |
| Short name | FITC Conjugated, Ubiquitin D Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, Ubiquitin D (Antibody to) |
| Alternative technique | antibodies |