Name : UCMA Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5711648967
| Long name | UCMA Primary Polyclonal Antibody |
| Also known as | UCMA PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | UCMA |
| Specificity | This is a highly specific antibody against UCMA |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UCMA |
| Gene ID number | 221044 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A furin-like protease processes UCMA into an N-terminal 37 amino acid peptide and a C-terminal 74 amino acid peptide, Introduction of recombinant Ucma-C interferes with osteogenic differentiation of mesenchymal stem cells, MC3T3-E1 preosteoblasts and primary osteoblasts, This suggests that Ucma may be involved in the negative regulation of osteogenic differentiation of osteochondrogenic precursor cells at the cartilage-bone interface and in peripheral zones of fetal cartilage, which is referred to as Unique cartilage matrix-associated protein C-terminal fragment (Ucma-C), UCMA is a 138 amino acid secreted protein that is highly expressed in resting chrondrocytes in developing long bones and is thought to function in the early phase of chrondrocyte differentiation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GRP, Gla rich protein, Gla-rich protein, Grp, OTTMUSP00000011599, RP23-272I15, UCMA, UCMA_HUMAN, Ucma-C, Unique cartilage matrix associated protein, Unique cartilage matrix-associated protein C-terminal fragment, Upper zone of growth plate and cartilage matrix associated, 1, C10orf49 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | UCMA |
| Short name | UCMA Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | UCMA (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25205 |
| Gene | UCMA |
| Long gene name | upper zone of growth plate and cartilage matrix associated |
| Synonyms gene | C10orf49 |
| Synonyms gene name | chromosome 10 open reading frame 49 |
| Locus | 10p13 |
| Discovery year | 2004-05-27 |
| GenBank acession | BC018068 |
| Entrez gene record | 221044 |
| Pubmed identfication | 12477932 |
| RefSeq identity | NM_145314 |
| Havana BLAST/BLAT | OTTHUMG00000017692 |