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UPA Antibody

UPA Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenUPA
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the UPA antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis UPA antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P00749
PurityPurified
Description A and B, Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain, Each consists of two chains, PLAU contains 1 EGF-like domain and 1 kringle domain, PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin, Structurally, The high molecular mass form contains a long chain A, The protein is found in high and low molecular mass forms, The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders, PLAU
ImmunogenA portion of amino acids 396-426 from the human protein was used as the immunogen for this UPA antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the UPA antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetUPA
Short nameUPA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameUPA (Antibody to)
Alternative techniqueantibodies
Identity 9052
Gene PLAU
Long gene name plasminogen activator, urokinase
Synonyms URK UPA
Locus 10q22, 2
Discovery year 2001-06-22
GenBank acession BC013575
Entrez gene record 5328
Pubmed identfication 2415429
RefSeq identity NM_002658
Havana BLAST/BLAT OTTHUMG00000018494
Locus Specific Databases LRG_593

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