Name : UPA Antibody
Supplier : NJS POLY
Price :406
SKU : GEN8269505199
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | UPA |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IF, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the UPA antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This UPA antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P00749 |
| Purity | Purified |
| Description | A and B, Cleavage occurs after residue 155 in the low molecular mass form to yield a short A1 chain, Each consists of two chains, PLAU contains 1 EGF-like domain and 1 kringle domain, PLAU specifically cleaves the Arg-|-Val bond in plasminogen to form plasmin, Structurally, The high molecular mass form contains a long chain A, The protein is found in high and low molecular mass forms, The protein is used in Pulmonary Embolism (PE) to initiates fibrinolysis, a member of the peptidase family S1, is a potent plasminogen activator and is clinically used for therapy of thrombolytic disorders, PLAU |
| Immunogen | A portion of amino acids 396-426 from the human protein was used as the immunogen for this UPA antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the UPA antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | UPA |
| Short name | UPA Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | UPA (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9052 |
| Gene | PLAU |
| Long gene name | plasminogen activator, urokinase |
| Synonyms | URK UPA |
| Locus | 10q22, 2 |
| Discovery year | 2001-06-22 |
| GenBank acession | BC013575 |
| Entrez gene record | 5328 |
| Pubmed identfication | 2415429 |
| RefSeq identity | NM_002658 |
| Havana BLAST/BLAT | OTTHUMG00000018494 |
| Locus Specific Databases | LRG_593 |