Name : USP11 (1220CT620.193.189) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN2463536906
| Long name | 189) Monoclonal Antibody, 193, USP11 (1220CT620 |
| Also known as | 189) Monoclonal Antibody, 193, USP11 (1220CT620 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | USP11 |
| Specificity | This is a highly specific antibody against USP11 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1220CT620, 189, 193 |
| Source | This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the C-terminal region of human USP11 |
| Gene ID number | 8237 |
| Swiss Prot | P51784 |
| Tested Applications | FCM, WB |
| Recommended dilutions | WB(1:1000), FC(1:25) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro) (PubMed:24724799), Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains, Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, Inhibits the degradation of target proteins by the proteasome (PubMed:12084015), Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:19874889), PubMed:20233726, PubMed:20233726), PubMed:24724799), and extremely low activity with 'Lys-27', Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Deubiquitinating enzyme 11, USP11, Ubiquitin carboxyl-terminal hydrolase 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11, UHX1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 189) Monoclonal, 193, USP11 (1220CT620 |
| Short name | 189) Monoclonal Antibody, 193, USP11 (1220CT620 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 189) monoclonal (Antibody to), 193, USP11 (1220CT620 |
| Alternative technique | antibodies |
| Identity | 12609 |
| Gene | USP11 |
| Long gene name | ubiquitin specific peptidase 11 |
| Synonyms gene name | ubiquitin specific protease 11 |
| Synonyms | UHX1 |
| Locus | Xp11, 3 |
| Discovery year | 1999-02-01 |
| GenBank acession | U44839 |
| Entrez gene record | 8237 |
| Pubmed identfication | 12838346 |
| RefSeq identity | NM_004651 |
| Classification | Ubiquitin specific peptidases |
| Havana BLAST/BLAT | OTTHUMG00000021437 |
| Locus Specific Databases | Mental Retardation database |