| Long name | VEGFB Primary Polyclonal Antibody |
| Also known as | VEGFB PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | VEGFB |
| Specificity | This is a highly specific antibody against VEGFB |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VEGFB |
| Gene ID number | 4902 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Several growth factors with angiogenic activity have been described and include fibroblast growth factor (FGF), The VEGF protein family is comprised of VEGF, VEGF-B, VEGF-B, VEGF-C and VEGF-D, VEGF-C binds to and specifically activates Flt-4 and Flk-1, all of which may exhibit angiogenic function in vivo, is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF, platelet derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs), which exists as two alternatively spliced isoforms known as VEGF-B167 and VEGF-B186, The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | VEGF B, VEGF related factor, VEGF-B, VEGFB, VEGFB_HUMAN, VEGFL, Vrf, vascular endothelial growth factor B isoform VEGFB-167 precursor, Vascular endothelial growth factor B |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | VEGFB |
| Short name | VEGFB Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | vascular endothelial growth factor B (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, VEGFB and IDBG-53284 and ENSG00000173511 and 7423, VEGFB and IDBG-643900 and ENSBTAG00000047567 and, VEGFL and VRF, Vegfb and IDBG-137732 and ENSMUSG00000024962 and 22340, protein heterodimerization activity, this GO :0001525 and angiogenesis and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0006493 and protein O-linked glycosylation and biological process this GO :0007507 and heart development and biological process this GO :0007596 and blood coagulation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0010629 and negative regulation of gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0035470 and positive regulation of vascular wound healing and biological process this GO :0042056 and chemoattractant activity and molecular function this GO :0042493 and response to drug and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043183 and vascular endothelial growth factor receptor 1 binding and molecular function this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050918 and positive chemotaxis and biological process this GO :0050930 and induction of positive chemotaxis and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060048 and cardiac muscle contraction and biological process this GO :0060754 and positive regulation of mast cell chemotaxis and biological process this GO :0060976 and coronary vasculature development and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0008201: heparin binding and also this GO :0042056: chemoattractant activity and also this GO :0042803: protein homodimerization activity and also this GO :0043183: vascular endothelial growth factor receptor 1 binding and also this GO :0046982: protein heterodimerization activity, this GO :0008083: growth factor activity, this GO :0008201: heparin binding, this GO :0042056: chemoattractant activity, this GO :0042803: protein homodimerization activity, this GO :0043183: vascular endothelial growth factor receptor 1 binding, this GO :0046982: protein heterodimerization activity, vascular endothelial growth factor B |
| Identity | 12681 |
| Gene | VEGFB |
| Long gene name | vascular endothelial growth factor B |
| Synonyms gene | VRF |
| Synonyms | VEGFL |
| Locus | 11q13, 1 |
| Discovery year | 1996-10-26 |
| GenBank acession | BC008818 |
| Entrez gene record | 7423 |
| Pubmed identfication | 8637916 8919691 |
| RefSeq identity | NM_003377 |
| Classification | VEGF family |
| Havana BLAST/BLAT | OTTHUMG00000167813 |
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