| Alternative name1 | API3, Apoptosis Inhibitor 3, BIRC4, Baculoviral IAP Repeat Containing 4, Baculoviral IAP Repeat-containing Protein 4, HILP, IAP 3, IAP-like Protein, IAP3, ILP-1, X-linked IAP, X-linked Inhibitor of Apoptosis Protein, Anti-XIAP (X Linked Inhibitor of Apoptosis |
| Alternative name2 | API3, Apoptosis Inhibitor 3, BIRC4, Baculoviral IAP Repeat Containing 4, Baculoviral IAP Repeat-containing Protein 4, HILP, IAP 3, IAP-like Protein, IAP3, ILP-1, X-linked IAP, X-linked Inhibitor of Apoptosis Protein, XIAP (X Linked Inhibitor of Apoptosis |
| Alternative name3 | API3, Apoptosis Inhibitor 3, BIRC4, Baculoviral IAP Repeat Containing 4, Baculoviral IAP Repeat-containing Protein 4, HILP, IAP 3, IAP-like Protein, IAP3, ILP-1, X-linked IAP, X-linked Inhibitor of Apoptosis Protein, XIAP (X Linked Inhibitor of Apoptosis |
| Alternative name4 | XIAP |
| Alternative name5 | API3, Apoptosis Inhibitor 3, BIRC4, Baculoviral IAP Repeat Containing 4, Baculoviral IAP Repeat-containing Protein 4, HILP, IAP 3, IAP-like Protein, IAP3, ILP-1, X-linked IAP, X-linked Inhibitor of Apoptosis Protein, Anti -XIAP (X Linked Inhibitor of Apoptosis |
| Other names | N/A, X-linked inhibitor of apoptosis |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N/A |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Mouse, Rat, Human |
| Specificity and cross-reactivity | It does not crossreact with other apoptosis inhibitors, Mouse and Rat, Species Crossreactivity: Crossreacts with Human, Detects the 53kD human XIAP protein |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | 1% BSA, containing 50% glycerol, pH 7, 2, Supplied as a liquid in PBS |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 3 months productone should be stored at -20 degrees Celsius, For long-term storage, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB) |
| Description | Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | API3, BIRC4, Baculoviral IAP Repeat 4, Baculoviral IAP Repeat Protein 4, HILP, IAP 3, IAP-like Protein, IAP3, ILP-1, Inhibitor 3, X-linked IAP, XIAP (X Linked Inhibitor of X-linked Inhibitor of Protein |
| Short name | API3, Apoptosis Inhibitor 3, BIRC4, Baculoviral IAP Repeat 4, Baculoviral IAP Repeat-containing Protein 4, HILP, IAP 3, IAP-like Protein, IAP3, ILP-1, X-linked IAP, X-linked Inhibitor of Apoptosis Protein, XIAP (X Linked Inhibitor of Apoptosis |
| Alternative name | API3, BIRC4, Baculoviral IAP Repeat Containing 4, Baculoviral IAP Repeat-containing Protein 4, HILP, IAP 3, IAP-like Protein, IAP3, ILP-1, X-linked IAP, X-linked suppressor on programmed cellular destruction Protein, programmed cellular destruction suppressor 3, X-linked inhibitor on apoptosis (X Linked suppressor on programmed cellular destruction |
| Alternative to gene target | XIAP and IDBG-85142 and ENSG00000101966 and 331, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, nuclei, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016055 and Wnt signaling pathway and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030510 and regulation of BMP signaling pathway and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0055070 and copper ion homeostasis and biological process this GO :0070424 and regulation of nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1902530 and positive regulation of protein linear polyubiquitination and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, X-linked inhibitor of apoptosis |
| Identity | 592 |
| Gene | XIAP |
| Long gene name | X-linked inhibitor of apoptosis |
| Synonyms gene | API3 BIRC4 |
| Synonyms gene name | E3 ubiquitin protein ligase , baculoviral IAP repeat-containing 4 X-linked inhibitor of apoptosis |
| Synonyms | hILP |
| Locus | Xq25 |
| Discovery year | 1998-06-10 |
| GenBank acession | U45880 |
| Entrez gene record | 331 |
| Pubmed identfication | 8552191 8654366 15749826 |
| RefSeq identity | NM_001167 |
| Classification | Baculoviral IAP repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000022336 |
| Locus Specific Databases | BIRC4base: Mutation registry for X-linked lymphoproliferative syndrome Mental Retardation database LRG_19 |
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