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XRCC5 Antibody

XRCC5 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenXRCC5
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, WB, IF
Recommended dilutionsFlow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the XRCC5 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis XRCC5 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P13010
PurityAntigen affinity
Description A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity, Ku is the DNA-binding component of the DNA-dependent protein kinase, This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events, The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5
ImmunogenA portion of amino acids 424-450 from the human protein was used as the immunogen for this XRCC5 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the XRCC5 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetXRCC5
Short nameXRCC5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameX-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, DNA-templated and biological process this GO :0007420 and brain development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016817 and hydrolase activity, DNA-templated and biological process this GO :0050769 and positive regulation of neurogenesis and biological process this GO :0051575 and 5'-deoxyribose-5-phosphate lyase activity and molecular function this GO :0060218 and hematopoietic stem cell differentiation and biological process this GO :0070419 and nonhomolo this GO us end joining complex and cellular component this GO :0071398 and cellular response to fatty acid and biological process this GO :0071475 and cellular hyperosmotic salinity response and biological process this GO :0071481 and cellular response to X-ray and biological process this GO :0075713 and establishment of integrated proviral latency and biological process, KARP-1 and KARP1 and KU80 and Ku86 and KUB2 and NFIV, XRCC5 and IDBG-80616 and ENSG00000079246 and 7520, Xrcc5 and IDBG-165686 and ENSMUSG00000026187 and 22596, acting on acid anhydrides, acting on acid anhydrides and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0042162: telomeric DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0044822: poly(A) RNA binding and also this GO :0051575: 5'-deoxyribose-5-phosphate lyase activity, acting on acid anhydrides and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032508 and DNA duplex unwinding and biological process this GO :0042162 and telomeric DNA binding and molecular function this GO :0042493 and response to drug and biological process this GO :0043234 and protein complex and cellular component this GO :0043564 and Ku70:Ku80 complex and cellular component this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, hydrolase activity, nuclei, telomeric region and cellular component this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003691 and double-stranded telomeric DNA binding and molecular function this GO :0004003 and ATP-dependent DNA helicase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006310 and DNA recombination and biological process this GO :0006351 and transcription, this GO :0000723 and telomere maintenance and biological process this GO :0000783 and nuclear telomere cap complex and cellular component this GO :0000784 and nuclear chromosome, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003684: damaged DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003691: double-stranded telomeric DNA binding and also this GO :0004003: ATP-dependent DNA helicase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008022: protein C-terminus binding and also this GO :0016817: hydrolase activity, this GO :0003684: damaged DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0003691: double-stranded telomeric DNA binding, this GO :0004003: ATP-dependent DNA helicase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008022: protein C-terminus binding, this GO :0016817: hydrolase activity, this GO :0031625: ubiquitin protein ligase binding, this GO :0042162: telomeric DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0044822: poly(A) RNA binding, this GO :0051575: 5'-deoxyribose-5-phosphate lyase activity, 88138 and IDBG-643715 and ENSBTAG00000010426 and 531945, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Identity 12833
Gene XRCC5
Long gene name X-ray repair cross complementing 5
Synonyms gene name 80kD) , Ku autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining
Synonyms KU80 KARP-1 Ku86 KUB2
Synonyms name 80kDa , Ku autoantigen
Locus 2q35
Discovery year 1992-01-22
GenBank acession AF039597
Entrez gene record 7520
Pubmed identfication 9636207 9214634
RefSeq identity NM_021141
Havana BLAST/BLAT OTTHUMG00000133059

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