Name : YKL39/CHI3L2 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5636968025
| Long name | ALEXA FLUOR 594 Conjugated, YKL39/CHI3L2 Polyclonal Antibody |
| Also known as | Anti-YKL39/CHI3L2 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | YKL39/CHI3L2 |
| Specificity | This is a highly specific antibody against YKL39/CHI3L2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human YKL39/CHI3L2 |
| Gene ID Number | 7690 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Additionally, Although related to bacterial chitinases, Highly expressed in chondrocytes (cartilage cells) and synoviocytes (fibroblastic cells that line joint cavities), Patients affected with rheumatoid arthritis (RA) have autoimmunity against YKL-39, YKL-39 binds glycan structures with high affinity, YKL-39 is upregulated in early degenerative cartilage diseases (such as RA) and may be a marker of chondrocyte activation in these autoimmune conditions, YKL-39 lacks the characteristic glutamate active site and, does not have enzymatic chitinase activity, suggesting that YKL-39 is involved in osteoarthritic and/or rheumatoid joint disease, thus, YKL-39 is a 390 amino acid cartilage protein that belongs to the chitinase family of chitin-fragmenting hydrolases |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | YKL-39 YKL39 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | YKL39/CHI3L2 |
| Short name | YKL39/CHI3L2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, YKL39/CHI3L2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1933 |
| Gene | CHI3L2 |
| Long gene name | chitinase 3 like 2 |
| Synonyms gene name | chitinase 3-like 2 |
| Locus | 1p13, 2 |
| Discovery year | 1994-12-20 |
| GenBank acession | U49835 |
| Entrez gene record | 1117 |
| Pubmed identfication | 8702629 |
| RefSeq identity | NM_004000 |
| Classification | Chitinases |
| Havana BLAST/BLAT | OTTHUMG00000012174 |