Filters

ZO-2 Antibody

ZO-2 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenZO-2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-F, IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the ZO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis ZO-2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UDY2
PurityAntigen affinity
Description Duclos et al, In the mouse inner ear, It lies about 70 kb centromeric to the X123 gene and is transcribed in the centromere-to-telomere direction, Itoh et al, Tight junction proteins (TJPs), Tjp2, Using in vitro assays and immunoprecipitation studies, Walsh et al, also known as Zona occludens 2 or ZO-2 is a protein that in humans is encoded by the TJP2 gene, and Tjp3 PDZ1 domains interacted with the C-terminal cytoplasmic domains of Cldn1 through Cldn8, belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions, or zonulae occludentes, (1994) mapped the gene telomeric to the Friedreich ataxia critical region on chromosome 9q13-q21, (1999) showed that the mouse Tjp1, (2010) found that Tjp2 expression decreased rapidly between E16, 5 and age 1 week to a level in adult mice that was approximately 50% of the level at birth(P0), Tight Junction Protein 2
ImmunogenA synthetic peptide corresponding to human Zona occludens 2 (SEHSKRGYYGQSARYRDTEL) was used as the immunogen for this ZO-2 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ZO-2 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetZO-2
Short nameZO-2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameZO-2 (Antibody to)
Alternative techniqueantibodies
Identity 11828
Gene TJP2
Long gene name tight junction protein 2
Synonyms gene DFNA51
Synonyms gene name autosomal dominant 51 , deafness
Synonyms ZO-2 X104 ZO2
Synonyms name Friedreich ataxia region gene X104 (tight junction protein ZO-2) zona occludens 2
Locus 9q21, 11
Discovery year 1999-07-01
GenBank acession L27476
Entrez gene record 9414
Pubmed identfication 7951235 20602916
RefSeq identity NM_201629
Classification Membrane associated guanylate kinases Deafness associated genes PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000019978

Similar products

Subscribe to our Newsletter