| Long name | ACE Primary Polyclonal Antibody |
| Also known as | ACE PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ACE |
| Specificity | This is a highly specific antibody against ACE |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Cell membrane, Secreted, Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from cat ACE1 |
| Gene ID number | 101094061 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, ACE exists in two forms, Also able to inactivate bradykinin, Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance, The germinal form is expressed by spermatozoa, The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), This enzyme plays a key role in the renin-angiotensin system, a 170KD somatic form and a 90KD germinal form, a potent vasodilatator, by some neuronal cells and variably by some macrophages and T lymphocytes, epithelial cells (especially in proximal renal tubules and small intestine), this results in an increase of the vasoconstrictor activity of angiotensin, Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ACE, ACE-1, ACE-T, ACE1, Angiotensin converting enzyme testis specic isoform, CD 143, Carboxycathepsin, DCP 1, Dipeptidyl carboxy peptidase 1, Dipeptidyl carboxypeptidase 1, Kininase II, MVCD3, Peptidase P, Peptidyl dipeptidase A, Testicular ECA, testis-specic isoform precursor, Angiotensin Converting Enzyme 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ACE |
| Short name | ACE Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Uncharacterized protein (Antibody to), Angiotensin-converting enzyme |
| Alternative technique | antibodies |
| Alternative to gene target | ACE and IDBG-728302 and ENSG00000264813 and, Plasma membranes, Uncharacterized protein, peptidyl-dipeptidase activity, this GO :0006508 and proteolysis and biological process this GO :0008237 and metallopeptidase activity and molecular function this GO :0008241 and peptidyl-dipeptidase activity and molecular function this GO :0016020 and membrane and cellular component, this GO :0008237: metallopeptidase activity, this GO :0008237: metallopeptidase activity and also this GO :0008241: peptidyl-dipeptidase activity, this GO :0008241: peptidyl-dipeptidase activity, Angiotensin-converting enzyme |
| Identity | 2707 |
| Gene | ACE |
| Long gene name | angiotensin I converting enzyme |
| Synonyms gene | DCP1 |
| Synonyms gene name | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| Synonyms | ACE1 CD143 |
| Synonyms name | peptidyl-dipeptidase A |
| Locus | 17q23, 3 |
| Discovery year | 1989-06-06 |
| GenBank acession | J04144 |
| Entrez gene record | 1636 |
| Pubmed identfication | 2554286 10319862 |
| Classification | CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000154927 |
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