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Acinus (Ser1180) Antibody

Acinus (Ser1180) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAcinus (Ser1180) Primary Polyclonal Antibody
Also known asAcinus (Ser1180) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAcinus Ser1180
Specificity The phosphorylation on Ser1180 is homologous to the phosphorylation at Ser1179 in mouse, This is a highly specific antibody against Acinus Ser1180
Modification(s)Phosphorylation
Modification site(s)Ser1180
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1150-1200/1341
Subcellular locationNucleus
SourceKLH conjugated synthetic phosphopeptide derived from human Acinus around the phosphorylation site of Ser1180
Gene ID number22985
Swiss ProtQ9UKV3
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ACIN1 confers RNA-binding to the complex, Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets, Induces apoptotic chromatin condensation after activation by CASP3, Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes), Regulates cyclin A1, The ASAP complex can inhibit RNA processing during in vitro splicing reactions, The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis, The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism, but not cyclin A2, expression in leukemia cells, specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S), the activity is different from the established EJC assembly and function, Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ACIN1, ACINUS, Apoptotic chromatin condensation inducer in the nucleus, KIAA0670, fSAP152, ACN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAcinus (Ser1180)
Short nameAcinus (Ser1180) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAcinus (Ser1180) (Antibody to)
Alternative techniqueantibodies

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