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ADAMTS8 Antibody

ADAMTS8 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameADAMTS8 Primary Polyclonal Antibody
Also known asADAMTS8 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenADAMTS8
SpecificityThis is a highly specific antibody against ADAMTS8
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAMTS8
Gene ID number11095
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 2, 3 and 4, ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, ADAMTS8 has a propeptide domain, ADAMTS8 is inhibited by the endogenous MMP inhibitors, In addition to the metalloprotease domain, TIMP1, The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, They have been demonstrated to have important roles in connective tissue organization, a Prohormone Convertase (PC, a cysteine rich domain and thrombospondin 1 like domains, and has been shown to be proteolytically active on a range of substrates, angiogenesis and cell migration, arthritis, but most efficiently by TIMP3, coagulation, furin) cleavage site, inflammation, the function of ADAMTS8 is still poorly understood, versican and brevican, A member of the metalloproteinase family containing disintegrin like domains (ADAMs), ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot 8, A disintegrin like and metalloprotease with thrombospondin type 1 mot 8, ADAM TS 8, ADAM TS8, ADAM metallopeptidase with thrombospondin type 1 mot 8, ADAMTS 8, ATS8_HUMAN, METH 2, METH 8, METH2, METH8, A disintegrin and metalloproteinase with thrombospondin mots 8
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetADAMTS8
Short nameADAMTS8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name 8 (Antibody to), ADAM metallopeptidase including thrombospondin classification 1 motif
Alternative techniqueantibodies
Alternative to gene target 8, ADAM-TS8 and METH2, ADAMTS8 and IDBG-642991 and ENSBTAG00000010411 and 512544, ADAMTS8 and IDBG-76259 and ENSG00000134917 and 11095, Adamts8 and IDBG-146397 and ENSMUSG00000031994 and 30806, Extracellular, low affinity phosphate transmembrane transporter activity, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0006508 and proteolysis and biological process this GO :0008201 and heparin binding and molecular function this GO :0008237 and metallopeptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009673 and low affinity phosphate transmembrane transporter activity and molecular function this GO :0031012 and extracellular matrix and cellular component this GO :0035435 and phosphate ion transmembrane transport and biological process, this GO :0004222: metalloendopeptidase activity, this GO :0004222: metalloendopeptidase activity and also this GO :0005178: integrin binding and also this GO :0008201: heparin binding and also this GO :0008237: metallopeptidase activity and also this GO :0008270: zinc ion binding and also this GO :0009673: low affinity phosphate transmembrane transporter activity, this GO :0005178: integrin binding, this GO :0008201: heparin binding, this GO :0008237: metallopeptidase activity, this GO :0008270: zinc ion binding, this GO :0009673: low affinity phosphate transmembrane transporter activity, ADAM metallopeptidase with thrombospondin type 1 motif
Identity 224
Gene ADAMTS8
Long gene name ADAM metallopeptidase with thrombospondin type 1 motif 8
Synonyms gene name 8 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif
Synonyms METH2 FLJ41712 ADAM-TS8
Locus 11q24, 3
Discovery year 1999-08-23
GenBank acession AF060153
Entrez gene record 11095
Pubmed identfication 10438512
RefSeq identity NM_007037
Classification ADAM metallopeptidases with thrombospondin type 1 motif
Havana BLAST/BLAT OTTHUMG00000165656

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