Name : ATX2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1167252016
| Long name | ATX2 Primary Polyclonal Antibody |
| Also known as | ATX2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ATX2 |
| Specificity | This is a highly specific antibody against ATX2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 770-820/1313 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATX2 |
| Gene ID number | 6311 |
| Swiss Prot | Q99700 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ADCA has been divided into three groups: ADCA types I-III, ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2, Clinically, Longer expansions result in earlier onset of the disease, There are four named isoforms, brain stem and spinal cord, bulbar and extrapyramidal signs, ophthalmoplegia, peripheral neuropathy and dementia, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ASL13, ATXN2, Ataxin-2, SCA2, Spinocerebellar ataxia type 2 protein, TNRC13, Trinucleotide repeat-containing gene 13 protein, ATX2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ATX2 |
| Short name | ATX2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ATX2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10555 |
| Gene | ATXN2 |
| Long gene name | ataxin 2 |
| Synonyms gene | SCA2 TNRC13 |
| Synonyms gene name | ataxin 2) , autosomal dominant, spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2 |
| Synonyms | ATX2 |
| Synonyms name | trinucleotide repeat containing 13 |
| Locus | 12q24, 12 |
| Discovery year | 1991-08-06 |
| GenBank acession | U80749 |
| Entrez gene record | 6311 |
| Pubmed identfication | 8358438 9225980 |
| RefSeq identity | NM_002973 |
| Classification | Ataxins Trinucleotide repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000133475 |
| Locus Specific Databases | LRG_864 |