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BACE1 (Ser498) Antibody

BACE1 (Ser498) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBACE1 (Ser498) Primary Polyclonal Antibody
Also known asBACE1 (Ser498) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBACE1 Ser498
SpecificityThis is a highly specific antibody against BACE1 Ser498
Modification(s)Phosphorylation
Modification site(s)Ser498
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human BACE1 around the phosphorylation site of Ser498
Gene ID number23621
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, Multiple transcript variants encoding different isoforms have been described for this gene, The encoded protein, [provided by RefSeq], a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi, one of which is the protein encoded by this gene, Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names APP beta secretase, ASP2, Asp 2, Aspartyl protease 2, BACE, BACE 1, BACE1 S498, BACE1_HUMAN, Beta secretase, Beta secretase 1, Beta site APP cleaving enzyme, Beta site APP cleaving enzyme 1, Beta site amyloid beta A4 precursor protein cleaving enzyme, Beta site amyloid precursor protein cleaving enzyme, Beta site amyloid precursor protein cleaving enzyme 1, Beta-secretase 1, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, FLJ90568, HSPC104, KIAA1149, Memapsin 2, Memapsin-2, Memapsin2, Membrane associated aspartic protease 2, Membrane-associated aspartic protease 2, Transmembrane aspartic proteinase Asp2, p-BACE1 Se498, p-BACE1 Ser498, BACE1 Ser498
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBACE1 (Ser498)
Short nameBACE1 (Ser498) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBACE1 (Ser498) (Antibody to)
Alternative techniqueantibodies
Identity 933
Gene BACE1
Long gene name beta-secretase 1
Synonyms gene BACE
Synonyms gene name beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1
Locus 11q23, 3
Discovery year 1999-10-29
GenBank acession AF190725
Entrez gene record 23621
Pubmed identfication 10531052
Havana BLAST/BLAT OTTHUMG00000160636

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