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Bcl-xL (Thr115) Antibody

Bcl-xL (Thr115) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBcl-xL (Thr115) Primary Polyclonal Antibody
Also known asBcl-xL (Thr115) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBcl-xL Thr115
SpecificityThis is a highly specific antibody against Bcl-xL Thr115
Modification(s)Phosphorylation
Modification site(s)Thr115
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range95-140/233
Subcellular location Mitochondrion, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human BCL2L1 around the phosphorylation site of Thr115
Gene ID number598
Swiss ProtQ07817
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis, Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, During synaptic stimulation, Inhibits activation of caspases, Isoform Bcl-X(L) also regulates presynaptic plasticity, Isoform Bcl-X(S) promotes apoptosis, from the mitochondrial membrane, including neurotransmitter release and recovery, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles, number of axonal mitochondria as well as size and number of synaptic vesicle clusters, Potent inhibitor of cell death
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Apoptosis regulator Bcl-X, BCL-XL/S, BCL2L, BCL2L1, BCLXL, BCLXS, Bcl-2-like protein 1, Bcl-X, Bcl2-L-1, PPP1R52, bcl-xL, bcl-xS, BCLX
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBcl-xL (Thr115)
Short nameBcl-xL (Thr115) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBcl-xL (Thr115) (Antibody to)
Alternative techniqueantibodies

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