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Bcl2 modifying factor Antibody

Bcl2 modifying factor Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBcl2 modifying factor Antibody
Also known asBcl2 modifying factor Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBcl2 modying factor
SpecificityThis is a highly specific antibody against Bcl2 modying factor
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bcl2 modifying factor
Gene ID number90427
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BID, Bad, Bcl-2 modifying factor (Bmf) is a BH3-only protein that binds prosurvival Bcl-2 family members to initiate apoptosis, Bik, Bim, Binding results in a caspase cascade leading to apoptosis, Bmf is sequestered to Myosin V motors on Actin in the cytoskeleton by associating with Dynein light chain 2 (DLC2) homodimers, Bmf is widely expressed in tissues such as pancreas, Bmf then translocates to the mitochondria, Hrk, If the cell undergoes loss of attachment (anoikis), NOXA, PUMA and Bmf, The BH3 domain of Bmf facilitates binding to a hydrophobic groove on the surface of Bcl-2, The gene encoding Bmf maps to chromosome 15q14, and in hematopoietic tissues, are proapoptotic members of the Bcl-2 family, liver and kidney, the cytoskeleton is disrupted and Bmf is released from DLC2, where Bcl-2 (an anti-apoptotic family member) is sequestered, which include Blk, The BH3-only proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BMF_HUMAN, Bcl-2-modying factor, Bcl2 modying factor, Bmf, FLJ00065, Bcl 2 modying factor
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description Complex subunit associated factors are involved in hybridoma growth, Eosinohils, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, Aplha
Gene targetBcl2 modifying factor
Short nameBcl2 modifying factor Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameB-cell CLL/lymphoma 2 modifying factor (Antibody to)
Alternative techniqueantibodies
Identity 24132
Gene BMF
Long gene name Bcl2 modifying factor
Synonyms FLJ00065
Locus 15q15, 1
Discovery year 2004-01-16
GenBank acession BC060783
Entrez gene record 90427
Pubmed identfication 11546872
RefSeq identity NM_033503
Classification BCL2 homology region 3 (BH3) only
Havana BLAST/BLAT OTTHUMG00000129875

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