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Bestrophin Antibody

Bestrophin Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBestrophin Primary Polyclonal Antibody
Also known asBestrophin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBestrophin
SpecificityThis is a highly specific antibody against Bestrophin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bestrophin
Gene ID number5068
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Best disease is frequently a reflection of mutations in the Bestrophin gene, Bestrophin Bestrophin 2, Human Bestrophin forms oligomeric chloride channels that are sensitive to intracellular calcium, Missense mutations at the Bestrophin locus reduces or abolishes Bestrophin protein mediated membrane current, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels, and Bestrophin 4 are transmembrane proteins that contain a high percentage of aromatic residues, is an early-onset autosomal dominant condition in which accumulation of lipofuscin-like material within and beneath the RPE leads to progressive loss of central vision, known as Best disease, which encodes a protein containing four putative transmembrane domains and localizes to the basolateral plasma membrane of RPE cells, Best vitelliform macular dystrophy, Bestrophin 3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BEST, BEST-1, BEST1, BEST1, BEST1_HUMAN, BMD, Best macular dystrophy, Bestrophin 1, Bestrophin-1, Bestrophin1, TU15B, VMD 2, VMD2, Vitellorm macular dystrophy, Vitellorm macular dystrophy 2, Vitellorm macular dystrophy protein 2, mBest1, BEST 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBestrophin
Short nameBestrophin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBestrophin (Antibody to)
Alternative techniqueantibodies
Identity 17106
Gene BEST4
Long gene name bestrophin 4
Synonyms gene VMD2L2
Synonyms gene name vitelliform macular dystrophy 2-like 2
Locus 1p34, 1
Discovery year 2003-12-03
GenBank acession AF440757
Entrez gene record 266675
Pubmed identfication 12032738 16702355
RefSeq identity NM_153274
Classification Bestrophins
Havana BLAST/BLAT OTTHUMG00000008488

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