Name : BIN2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5685307031
| Long name | BIN2 Primary Polyclonal Antibody |
| Also known as | BIN2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | BIN2 |
| Specificity | This is a highly specific antibody against BIN2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BIN2/BRAP1 |
| Gene ID number | 51411 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis, BIN1 also interacts with the transcription factors c-Myc and MyoD, BIN1 and BIN2 are BAR proteins that share 61% sequence similarity, BIN2, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region, BIN2 shows preferred expression in tissues of hematopoietic origin, In contrast to BIN1, There are two isoforms of BIN2 that are produced as a result of alternative splicing events, also known as Breast cancer-associated protein 1, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes, colon, is a 565 amino acid protein that interacts with BIN1, lymphoid and granulocytic cells, placenta, potentially functioning as a tumor suppressor, thymus, with high levels found in spleen, BAR proteins are characterized by a common N-terminal BAR (bin |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BIN2_HUMAN, BRAP 1, Breast cancer associated protein BRAP1, Breast cancer-associated protein 1, Bridging integrator 2, BIN2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BIN2 |
| Short name | BIN2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | BIN2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1053 |
| Gene | BIN2 |
| Long gene name | bridging integrator 2 |
| Synonyms | BRAP-1 |
| Locus | 12q13, 13 |
| Discovery year | 2000-05-25 |
| GenBank acession | AF146531 |
| Entrez gene record | 51411 |
| Pubmed identfication | 10903846 |
| Classification | N-BAR domain containing |
| Havana BLAST/BLAT | OTTHUMG00000185197 |