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C5a Antibody

C5a Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenC5a
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Rat
Tested applicationsWB
Recommended dilutions1-0, 5ug/ml, Western blot: 0
NotesOptimal dilution of the C5a antibody should be determined by the researcher
Intented useThis C5a antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P08650
PurityAntigen affinity
Description An activation peptide, C5a, Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis, Mutations in this gene cause complement component 5 deficiency, The C5b macromolecular cleavage product can form a complex with the C6 complement component, The protein encoded by this gene is the fifth component of complement, This gene is mapped to 9q33, This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge, a disease where patients show a propensity for severe recurrent infections, and this complex is the basis for formation of the membrane attack complex, is derived from the alpha polypeptide via cleavage with a convertase, which includes additional complement components, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, which plays an important role in inflammatory and cell killing processes, 2, C5a is a protein fragment released from complement component C5
ImmunogenAmino acids TIADKIRKESHHKGMLLGR of rat C5a were used as the immunogen for the C5a antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the C5a antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetC5a
Short nameC5a Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameC5a (Antibody to)
Alternative techniqueantibodies
Identity 1331
Gene C5
Long gene name complement C5
Synonyms gene name complement component 5
Synonyms CPAMD4 C5a C5b
Synonyms name prepro-C5 C5a anaphylatoxin
Locus 9q33, 2
Discovery year 2001-06-22
GenBank acession M57729
Entrez gene record 727
RefSeq identity NM_001735
Classification Endogenous ligands Complement system C3 and PZP like, alpha-2-macroglobulin domain containing
Havana BLAST/BLAT OTTHUMG00000020579
Locus Specific Databases C5base: Mutation registry for C5 deficiency LRG_28

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