Name : CBL2 (Tyr674) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN5913588060
| Long name | CBL2 (Tyr674) Primary Polyclonal Antibody |
| Also known as | CBL2 (Tyr674) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CBL2 Tyr674 |
| Specificity | This is a highly specific antibody against CBL2 Tyr674 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Tyr674 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human C CBL around the phosphorylation site of Tyr674 |
| Gene ID number | 867 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as an E3 ubiquitin-protein ligase, Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface, EGF and CSF1, Recognizes activated receptor tyrosine kinases, and terminates signaling, and then transfers it to substrates promoting their degradation by the proteasome, including PDGFA, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, Participates in signal transduction in hematopoietic cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | C CBL, CBL 2, CBL2, CBL2 Tyr674, CBL2 Y674, CBL_HUMAN, Cas Br M murine ecotropic retroviral transforming sequence, Cas-Br-M murine ecotropic retroviral transforming sequence, Casitas B lineage lymphoma proto oncogene, Casitas B-lineage lymphoma proto-oncogene, E3 ubiquitin protein ligase CBL, E3 ubiquitin-protein ligase CBL, Oncogene CBL2, Proto oncogene c CBL, Proto-oncogene c-CBL, RGD1561386, RING finger protein 55, RNF55, Signal transduction protein CBL, cbl, p-CBL2 Tyr674, p-CBL2 Y674, C CBL Tyr674 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CBL2 (Tyr674) |
| Short name | CBL2 (Tyr674) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CBL2 (Tyr674) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1541 |
| Gene | CBL |
| Long gene name | Cbl proto-oncogene |
| Synonyms gene | CBL2 |
| Synonyms gene name | Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase |
| Synonyms | RNF55 c-Cbl |
| Synonyms name | oncogene CBL2 |
| Locus | 11q23, 3 |
| Discovery year | 1989-06-30 |
| GenBank acession | X57110 |
| Entrez gene record | 867 |
| Pubmed identfication | 2013228 |
| RefSeq identity | NM_005188 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000166170 |
| Locus Specific Databases | LRG_608 |