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CBL2 (Tyr731) Antibody

CBL2 (Tyr731) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCBL2 (Tyr731) Primary Polyclonal Antibody
Also known asCBL2 (Tyr731) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCBL2 Tyr731
SpecificityThis is a highly specific antibody against CBL2 Tyr731
Modification(s)Phosphorylation
Modification site(s)Tyr731
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human CBL2 around the phosphorylation site of Tyr731
Gene ID number867
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen An additional mechanism to attenuate receptor signaling is thought to be achieved by CBLâ, In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling, Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families, The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, such as PI 3K and Vav, thus attenuating the signal of receptors, &euro, &trade, The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice, s interaction with downstream targets of tyrosine kinases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 4732447J05Rik, C CBL, CBL 2, CBL2 Tyr731, CBL2 Tyr731, CBL_HUMAN, Cas-Br-M murine ecotropic retroviral transforming sequence, Casitas B lineage lymphoma proto oncogene, Oncogene CBL2, Proto oncogene c CBL, RGD1561386, RING finger protein 55, RNF55v Signal transduction protein CBL, p-CBL2 Tyr731, p-CBL2 Y731, C CBL Tyr731, E3 ubiquitin protein ligase CBL
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCBL2 (Tyr731)
Short nameCBL2 (Tyr731) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCBL2 (Tyr731) (Antibody to)
Alternative techniqueantibodies
Identity 1541
Gene CBL
Long gene name Cbl proto-oncogene
Synonyms gene CBL2
Synonyms gene name Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase
Synonyms RNF55 c-Cbl
Synonyms name oncogene CBL2
Locus 11q23, 3
Discovery year 1989-06-30
GenBank acession X57110
Entrez gene record 867
Pubmed identfication 2013228
RefSeq identity NM_005188
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000166170
Locus Specific Databases LRG_608

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