| Also known as | CD11b |
| Other names | CD11 antigen-like family member B, CD11 antigen-like family member B, CD_antigen: CD11b, CR-3 alpha chain, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Integrin alpha-M, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, alpha M (complement component 3 receptor 3 subunit), antigen CD11b (p170), cell surface glycoprotein MAC-1 subunit alpha, integrin, integrin alpha-M, leukocyte adhesion receptor MO1, macrophage antigen alpha polypeptide, neutrophil adherence receptor alpha-M subunit, integrin alpha-M isoform 2 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | ITGAM |
| Gene name synonims | N/A |
| Other gene names | CD11B, CD11B, CR3A, CR3A, ITGAM, MAC-1, MAC1A, MO1A, SLEB6, ITGAM |
| Clonality | Monoclonal |
| Immunoglobulin isotype | kappa, IgG2b |
| Clone | M1/70 |
| Host organism | Rat (Rattus norvegicus) |
| Species reactivity | Baboon, Chimpanzee, Cynomolgus, Due to limited knowledge and inability for testing each and every species, Rabbit (Oryctolagus cuniculus) and Mouse (Mus musculus), Rhesus, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Integrin å, Integrin å, Integrins are heterodimeric proteins that contain an a chain and b chain, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, and also in the phagocytosis of complement coated particles, or inactivated-C3b (iC3b) receptor 3 (CR3), CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands, M combines with the Integrin ?2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), M/?2 is important in the adherence of neutrophils and monocytes to stimulated endothelium |
| Purification method | N/A |
| Form/Appearance | N/A |
| Concentration | N/A |
| Storage and shipping | Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications: | Flow Cytometry (FC/FACS), Functional Studies , Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), ELISA (EIA) |
| Gene target | CD11b |
| Short name | CD11b |
| Alternative name | CD11b |
| Identity | 1626 |
| Gene | CD11B |
| Long gene name | integrin subunit alpha M |
| Synonyms gene | CR3A |
| Synonyms gene name | alpha, alpha M (complement component 3 receptor 3 subunit) , alpha M (complement component receptor 3, also known as CD11b (p170), integrin, macrophage antigen alpha polypeptide) integrin |
| Synonyms | MAC-1 CD11b ITGAM |
| Synonyms name | complement component 3 receptor 3 subunit |
| Locus | 16p11, 2 |
| Discovery year | 1988-08-05 |
| GenBank acession | J03925 |
| Entrez gene record | 3684 |
| RefSeq identity | NM_000632 |
| Classification | Complement system Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000176612 |