| Long name | CD14 Primary Polyclonal Antibody |
| Also known as | CD14 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD14 |
| Specificity | This is a highly specific antibody against CD14 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 240-270/366 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from mouse CD14 |
| Gene ID number | 12475 |
| Swiss Prot | P10810 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts via MyD88, TIRAP and TRAF6, Up-regulates cell surface molecules, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, cytokine secretion and the inflammatory response, including adhesion molecules (By similarity), leading to NF-kappa-B activation, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS), In concert with LBP |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CD14, Myeloid cell-specific leucine-rich glycoprotein, Monocyte differentiation antigen CD14 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD14 |
| Short name | CD14 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD14 molecule (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CD14 and IDBG-49157 and ENSG00000170458 and 929, CD14 and IDBG-646064 and ENSBTAG00000015032 and 281048, Cd14 and IDBG-138525 and ENSMUSG00000051439 and 12475, Extracellular, lipoteichoic acid binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0001847 and opsonin receptor activity and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006909 and pha this GO cytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0009408 and response to heat and biological process this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0016019 and peptidoglycan receptor activity and molecular function this GO :0031225 and anchored component of membrane and cellular component this GO :0032026 and response to magnesium ion and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045471 and response to ethanol and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070891 and lipoteichoic acid binding and molecular function this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process, this GO :0001530: lipopolysaccharide binding, this GO :0001530: lipopolysaccharide binding and also this GO :0001847: opsonin receptor activity and also this GO :0005515: protein binding and also this GO :0016019: peptidoglycan receptor activity and also this GO :0070891: lipoteichoic acid binding, this GO :0001847: opsonin receptor activity, this GO :0005515: protein binding, this GO :0016019: peptidoglycan receptor activity, this GO :0070891: lipoteichoic acid binding, CD14 molecule |
| Identity | 1628 |
| Gene | CD14 |
| Long gene name | CD14 molecule |
| Synonyms gene name | CD14 antigen |
| Locus | 5q31, 3 |
| Discovery year | 1988-05-31 |
| Entrez gene record | 929 |
| Pubmed identfication | 2472171 2462937 |
| RefSeq identity | NM_000591 |
| Classification | CD molecules Scavenger receptors |
| Havana BLAST/BLAT | OTTHUMG00000129507 |