| Also known as | CD68 |
| Other names | CD68 antigen, CD68 molecule, CD_antigen: CD68, Gp110, Macrosialin, macrophage antigen CD68, macrosialin, member 1, scavenger receptor class D, macrosialin isoform B |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | CD68 |
| Gene name synonims | N/A |
| Other gene names | CD68, GP110, LAMP4, N/A, SCARD1, CD68 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | kappa, IgG1 |
| Clone | SPM130 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Cat, Does not react with pig, Due to limited knowledge and inability for testing each and every species, Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus), and chicken, dog, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | It also reacts with plasmacytoid T cells, It is important for identifying macrophages in tissue sections, It reacts with myeloid precursors and peripheral blood granulocytes, It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia, It stains macrophages in a wide variety of human tissues, Lymphomas are negative or show few granules, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, and in bone marrow, in lamina propria of the gut, in lung alveoli, including Kupffer cells and macrophages in the red pulp of the spleen, which are supposed to be of monocyte/macrophage origin, which is identified as CD68, This antibody recognizes a glycoprotein of 110kDa |
| Purification method | N/A |
| Form/Appearance | N/A |
| Concentration | N/A |
| Storage and shipping | Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications: | Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Gene target | CD68 |
| Short name | CD68 |
| Alternative name | CD68 molecule |
| Alternative to gene target | CD68 and IDBG-25923 and ENSG00000129226 and 968, CD68 and IDBG-635034 and ENSBTAG00000000133 and 504960, Cd68 and IDBG-191443 and ENSMUSG00000018774 and 12514, GP110 and LAMP4 and SCARD1, Plasma membranes, this GO :0005765 and lysosomal membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0071310 and cellular response to organic substance and biological process, CD68 molecule |
| Identity | 1693 |
| Gene | CD68 |
| Long gene name | CD68 molecule |
| Synonyms gene name | CD68 antigen |
| Synonyms | SCARD1 macrosialin GP110 DKFZp686M18236 LAMP4 |
| Synonyms name | member 1 CD68 antigen macrophage antigen CD68 , scavenger receptor class D |
| Locus | 17p13, 1 |
| Discovery year | 1993-06-11 |
| GenBank acession | S57235 |
| Entrez gene record | 968 |
| Pubmed identfication | 9790779 |
| RefSeq identity | NM_001251 |
| Classification | CD molecules Scavenger receptors |
| Havana BLAST/BLAT | OTTHUMG00000108146 |