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CLCA3 Antibody

CLCA3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCLCA3 Primary Polyclonal Antibody
Also known asCLCA3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCLCA3
SpecificityThis is a highly specific antibody against CLCA3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse CLCA3
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Rat, Mouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins, CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins, CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis, CLCA2 expression is downregulated in breast cancer, CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein, CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach, display distinct tissue distribution patterns, therefore CLCA2 is thought to act as a tumor suppressor in normal cells, which includes the human homologs CLCA1 and CLCA2, The calcium-activated chloride channel (CLCA) protein family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CLCA3P, Calcium-activated chloride channel regulator family member 3, Chloride channel accessory 3 pseudogene, Chloride channel calcium activated family member 3, Clca1, Clca2, Gob 5, Gob-5, Gob5, MGC143984, MGC143985, chloride channel calcium activated 3, hCLCA3, mCLCA3, Calcium activated chloride channel 3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCLCA3
Short nameCLCA3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCLCA3 (Antibody to)
Alternative techniqueantibodies
Identity 2017
Gene CLCA3P
Long gene name chloride channel accessory 3, pseudogene
Synonyms gene CLCA3
Synonyms gene name calcium activated, chloride channel, family member 3 chloride channel regulator 3
Locus 1p22, 3
Discovery year 1998-10-02
GenBank acession AF043976
Entrez gene record 9629
Pubmed identfication 10095065
RefSeq identity NM_004921
Classification Chloride channel accessory
Havana BLAST/BLAT OTTHUMG00000010258

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