Name : Cullin 7 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5255142940
| Long name | Cullin 7 Primary Polyclonal Antibody |
| Also known as | Cullin 7 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Cullin 7 |
| Specificity | This is a highly specific antibody against Cullin 7 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cullin 7 |
| Gene ID number | 9820 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, In vitro, Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity), Seems not to promote polyubiquitination and proteasomal degradation of TP53, Skeletal changes include long slender tubular bones and tall vertebral bodies, and normal intelligence and endocrine function, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity, facial dysmorphism, large head circumference, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, Component of a probable SCF-like E3 ubiquitin-protein ligase complex, Involvement in disease: Defects in CUL7 are the cause of 3M syndrome type 1 (3M1) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CUL7, CUL7_HUMAN, Cullin-7, KIAA0076, dJ20C7, 5, CUL-7 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Cullin 7 |
| Short name | Cullin 7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Cullin 7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 21024 |
| Gene | CUL7 |
| Long gene name | cullin 7 |
| Synonyms gene | KIAA0076 |
| Synonyms gene name | KIAA0076 |
| Synonyms | dJ20C7, 5 |
| Locus | 6p21, 1 |
| Discovery year | 2003-11-21 |
| GenBank acession | BC033647 |
| Entrez gene record | 9820 |
| Pubmed identfication | 12481031 12904573 |
| RefSeq identity | NM_014780 |
| Classification | Cullins |
| Havana BLAST/BLAT | OTTHUMG00000014718 |