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CXCR6/BONZO Antibody

CXCR6/BONZO Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCXCR6/BONZO Primary Polyclonal Antibody
Also known asCXCR6/BONZO PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCXCR6/BONZO
SpecificityThis is a highly specific antibody against CXCR6/BONZO
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range141-164/342
Subcellular location Transmembrane, Helical
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CXCR6
Gene ID number10663
Swiss ProtO00574
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes, During progression of the infection, HIV1 infection relies upon interaction with a chemokine receptor, SIV also utilizes CCR5 in the early stages of infection, They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR), but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15), the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4), usually chemokine (C-C) receptor 5 (CCR5), Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C-X-C chemokine receptor type 6, CD186, CDw186, CXC-R6, CXCR-6, CXCR6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR, BONZO
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCXCR6/BONZO
Short nameCXCR6/BONZO Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namechemokine (C-X-C motif) receptor 6/BONZO (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BONZO and CD186 and STRL33 and TYMSTR, C-X-C chemokine receptor activity, CXCR6 and IDBG-29993 and ENSG00000172215 and 10663, CXCR6 and IDBG-646261 and ENSBTAG00000015708 and 506807, Cxcr6 and IDBG-206490 and ENSMUSG00000048521 and 80901, Plasma membranes, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019079 and viral genome replication and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0015026: coreceptor activity and also this GO :0016494: C-X-C chemokine receptor activity, this GO :0015026: coreceptor activity, this GO :0016494: C-X-C chemokine receptor activity, chemokine (C-X-C motif) receptor 6
Identity 16647
Gene CXCR6
Long gene name C-X-C motif chemokine receptor 6
Synonyms gene name chemokine (C-X-C motif) receptor 6
Synonyms TYMSTR STRL33 BONZO CD186
Locus 3p21, 31
Discovery year 2002-08-23
GenBank acession AF007545
Entrez gene record 10663
Pubmed identfication 9166430 9230441
Classification CD molecules C-X-C motif chemokine receptors
Havana BLAST/BLAT OTTHUMG00000133448

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