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DEPTOR Antibody

DEPTOR Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDEPTOR Primary Polyclonal Antibody
Also known asDEPTOR PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDEPTOR
SpecificityThis is a highly specific antibody against DEPTOR
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range62-107/409
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DEPTOR/DEPDC6
Gene ID number64798
Swiss ProtQ8TB45
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Chromosome 8 consists of nearly 146 million base pairs, Containing two DEP domains and one PDZ (DHR) domain, DEPTOR interacts with FRAP via its PDZ domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24, Pfeiffer syndrome, Schizophrenia, Trisomy 8, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8, also known as DEP, and undergoes post-translational phosphorylation, bipolar disorder, congenital hypothyroidism, encodes over 800 genes and is associated with a variety of diseases and malignancies, is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways, 12, 6 or DEPDC6 (DEP domain-containing protein 6), DEPTOR (DEP domain containing MTOR-interacting protein)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6, DEPDC6, DEPTOR, 6, DEP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDEPTOR
Short nameDEPTOR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDEP domain containing Mammalian target on rapamycin-interacting protein (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, DEPTOR and IDBG-34051 and ENSG00000155792 and 64798, Deptor and IDBG-141160 and ENSMUSG00000022419 and 97998, multiple, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0045792 and negative regulation of cell size and biological process this GO :2001236 and regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, 28648 and IDBG-645663 and ENSBTAG00000015341 and 617606, DEP domain containing MTOR-interacting protein
Identity 22953
Gene DEPTOR
Long gene name DEP domain containing MTOR interacting protein
Synonyms gene DEPDC6
Synonyms gene name DEP domain containing 6
Synonyms DEP, 6 FLJ12428
Locus 8q24, 12
Discovery year 2004-02-23
Entrez gene record 64798
Pubmed identfication 19446321
RefSeq identity NM_022783
Classification PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000165052

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