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DMPK Antibody

DMPK Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDMPK Primary Polyclonal Antibody
Also known asDMPK PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDMPK
SpecificityThis is a highly specific antibody against DMPK
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DMPK
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DM arises through expansion of CTG repeats in the 3â, DMPK is implicated in myotonic muscular dystrophy (DM), L-type calcium channels, Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus (5), Other substrates for DMPK include myogenin, These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction (2, and Phospholemman (PLM) (1), to mediate in part the DM phenotype (6), &euro, &trade, -UTR of the DMPK gene (4), 3), Myotonic dystrophy protein kinase is a multi-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis (1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DM, DM 1, DM kinase, DM protein kinase, DM-kinase, DM1, DM1 protein kinase, DM1PK, DMK, DMPK, DMPK_HUMAN, Dystrophia myotonica 1, Dystrophia myotonica protein kinase, MDPK, MT PK, MT-PK, Myotonic dystrophy associated protein kinase, Myotonic dystrophy protein kinase, Myotonin protein kinase, Myotonin protein kinase A, Myotonin-protein kinase, Thymopoietin homolog, Dystrophia myotonica protein kinase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDMPK
Short nameDMPK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDMPK (Antibody to)
Alternative techniqueantibodies
Identity 2933
Gene DMPK
Long gene name dystrophia myotonica protein kinase
Synonyms gene DM1 DM
Synonyms gene name dystrophia myotonica 1 (includes dystrophia myotonia protein kinase)
Synonyms DMK DM1PK MDPK MT-PK
Synonyms name dystrophia myotonica 1 DM protein kinase myotonin protein kinase A myotonic dystrophy associated protein kinase thymopoietin homolog
Locus 19q13, 32
Discovery year 1997-10-10
GenBank acession L19268
Entrez gene record 1760
Pubmed identfication 1546325 1546326
RefSeq identity NM_004409
Havana BLAST/BLAT OTTHUMG00000182334

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