Dnmt1 Antibody

Dnmt1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	Dnmt1 Primary Polyclonal Antibody
Also known as	Dnmt1 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	Dnmt1
Specificity	This antibody will not recongize isoform 3, This is a highly specific antibody against Dnmt1
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen range	10-60/1616
Subcellular location	Nucleus
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt1
Gene ID number	1786
Swiss Prot	P26358
Tested Applications	IF(IHC-P), IHC-P
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication, DNA methylation is coordinated with methylation of histones, In association with DNMT3B and via the recruitment of CTCFL/BORIS, It is responsible for maintaining methylation patterns established in development, Mediates transcriptional repression by direct binding to HDAC2, Preferentially methylates hemimethylated DNA, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9, that is essential for epigenetic inheritance, Methylates CpG residues
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	ADCADN, CXXC-type zinc finger protein 9, CXXC9, DNA (cytosine-5)-methyltransferase 1, DNA MTase HsaI, DNA methyltransferase HsaI, DNMT, Dnmt1, HSN1E, M, MCMT, AIM, HsaI
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	Dnmt1
Short name	Dnmt1 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	Dnmt1 (Antibody to)
Alternative technique	antibodies
Identity	2975
Gene	DNMT
Long gene name	DNA methyltransferase 1
Synonyms gene name	DNA (cytosine-5-)-methyltransferase 1
Synonyms	MCMT CXXC9 DNMT1
Locus	19p13, 2
Discovery year	1991-06-04
GenBank acession	X63692
Entrez gene record	1786
Pubmed identfication	1594447
RefSeq identity	NM_001379
Classification	Zinc fingers CXXC-type
Havana BLAST/BLAT	OTTHUMG00000180397
Locus Specific Databases	LRG_362

Dnmt1 Antibody

Dnmt1 Antibody size: 0.1ml 263

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