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Dnmt2 Antibody

Dnmt2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDnmt2 Primary Polyclonal Antibody
Also known asDnmt2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDnmt2
SpecificityThis is a highly specific antibody against Dnmt2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dnmt2
Gene ID number1787
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3, DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, Dnmt1 is the most abundant, Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, Dnmt3a and Dnmt3b are encoded by two distinct genes, The Dnmt enzymes are encoded by independent genes, and is likely involved in methylating newly integrated retroviral DNA, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development, and this methylation results in transcriptional repression of the target gene, but both are abundantly expressed in embryonic stem cells, is expressed at substantially lower levels in adult tissues, where they also methylate CpG motifs on DNA, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DNA 5 cytosine methyltransferase, DNA MTase homolog HsaIIP, DNA cytosine 5 methyltransferase 2, DNA cytosine 5 methyltransferase like protein 2, DNA cytosine-5-methyltransferase-like protein 2, DNA methyltransferase 2, DNA methyltransferase homolog HsaIIP, DmMT 2, DmMT2, Dnmt 2, Dnmt2, M, MHsaIIP, OTTHUMP00000045198, PuMet, RNMT 1, RNMT1, TRDMT 1, TRDMT1, TRDMT_HUMAN, nmt 2, nmt2, tRNA aspartic acid methyltransferase 1, tRNA aspartic acid methyltransferase 1 variant 1, tRNA aspartic acid methyltransferase 1 variant 2, tRNA aspartic acid methyltransferase 1 variant 3, tRNA aspartic acid methyltransferase 1 variant 4, tRNA aspartic acid methyltransferase 1 variant 5, tRNA aspartic acid methyltransferase 1 variant 8, tRNA cytosine 5 methyltransferase, tRNA cytosine38-C5-methyltransferase, HsaIIP, dDNMT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDnmt2
Short nameDnmt2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDnmt2 (Antibody to)
Alternative techniqueantibodies
Identity 2977
Gene TRDMT1
Long gene name tRNA aspartic acid methyltransferase 1
Synonyms gene DNMT2
Synonyms gene name DNA (cytosine-5-)-methyltransferase 2
Synonyms RNMT1
Synonyms name tRNA (cytosine(38)-C(5))-methyltransferase
Locus 10p13
Discovery year 1998-05-07
GenBank acession AJ223333
Entrez gene record 1787
Pubmed identfication 9425235 9763678 16424344
RefSeq identity NM_004412
Havana BLAST/BLAT OTTHUMG00000017745

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