Name : DTX2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5935936092
| Long name | DTX2 Primary Polyclonal Antibody |
| Also known as | DTX2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DTX2 |
| Specificity | This is a highly specific antibody against DTX2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DTX2 |
| Gene ID number | 113878 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | DTX2 also functions as an ubiquitin ligase protein in vitro, DTX2 is a regulator of Notch signaling, It contains one RING-type zinc finger and two WWE domains, It probably acts both as a positive and negative regulator of Notch, The WWE domains are thought to mediate some protein-protein interaction, There are two named isoforms, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations, and are frequently found in ubiquitin ligases, depending on the developmental and cell context, mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity, DTX2 belongs to the Deltex family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DTX2_HUMAN, Deltex2, Highly similar to hPMSR6 [H, Protein deltex 2, RING finger protein 58, RNF58, Zinc ion binding protein, hDTX2, Deltex 2, sapiens] |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DTX2 |
| Short name | DTX2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | DTX2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15973 |
| Gene | DTX2 |
| Long gene name | deltex E3 ubiquitin ligase 2 |
| Synonyms gene name | E3 ubiquitin ligase , deltex (Drosophila) homolog 2 deltex homolog 2 (Drosophila) deltex 2 |
| Synonyms | RNF58 KIAA1528 |
| Locus | 7q11, 23 |
| Discovery year | 2001-08-13 |
| Entrez gene record | 113878 |
| Pubmed identfication | 12670957 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000162594 |