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DUOXA2 Antibody

DUOXA2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDUOXA2 Primary Polyclonal Antibody
Also known asDUOXA2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDUOXA2
SpecificityThis is a highly specific antibody against DUOXA2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DUOXA2
Gene ID number405753
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Angelman syndrome, DUOXA2 is essential for the maturation and transport of DUOX2 from the ER to the plasma membrane and is also thought to play a role in the synthesis of thyroid hormone (TH), Defects in the DUOXA2 gene are associated with the pathogenesis of congenital hypothyroidism, Expressed specifically in thyroid and salivary glands, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes, The gene encoding DUOXA2 maps to human chromosome 15, a disorder that affects infants and is characterized by a significant decrease or a complete deficiency of TH from birth, which houses over 700 genes and comprises nearly 3% of the human genome, DUOXA2 is a 320 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum (ER) and belongs to the DUOXA family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DOXA2_HUMAN, Dual oxidase activator 2, Dual oxidase maturation factor 2, Dual oxidase maturation factor-2, SIMNIPHOM, TDH5, Dual oxidase activator 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDUOXA2
Short nameDUOXA2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDUOXA2 (Antibody to)
Alternative techniqueantibodies
Identity 32698
Gene DUOXA2
Long gene name dual oxidase maturation factor 2
Locus 15q21, 1
Discovery year 2006-05-16
GenBank acession BX537581
Entrez gene record 405753
Pubmed identfication 16651268
RefSeq identity NM_207581
Havana BLAST/BLAT OTTHUMG00000131354

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