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DUSP6 Antibody

DUSP6 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDUSP6
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the DUSP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis DUSP6 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q16828
PurityAntigen affinity
Description Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, SAPK/JNK, These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues, They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, This gene product inactivates ERK2, Two transcript variants encoding different isoforms have been found for this gene, and different modes of inducibility of their expression by extracellular stimuli, and unlike most other members of this family, different tissue distribution and subcellular localization, is expressed in a variety of tissues with the highest levels in heart and pancreas, is localized in the cytoplasm, p38), which are associated with cellular proliferation and differentiation, The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily
ImmunogenA portion of amino acids 59-88 from the human protein was used as the immunogen for this DUSP6 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DUSP6 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDUSP6
Short nameDUSP6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namedual specificity phosphatase 6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DUSP6 and IDBG-50524 and ENSG00000139318 and 1848, DUSP6 and IDBG-630730 and ENSBTAG00000004587 and 515310, Dusp6 and IDBG-187794 and ENSMUSG00000019960 and 67603, HH19 and MKP3 and PYST1, MAP kinase tyrosine/serine/threonine phosphatase activity, nuclei, this GO :0000188 and inactivation of MAPK activity and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004721 and phosphoprotein phosphatase activity and molecular function this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0008138 and protein tyrosine/serine/threonine phosphatase activity and molecular function this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0010033 and response to organic substance and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0017017 and MAP kinase tyrosine/serine/threonine phosphatase activity and molecular function this GO :0030154 and cell differentiation and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0040036 and regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0042663 and regulation of endodermal cell fate specification and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051409 and response to nitrosative stress and biological process this GO :0060420 and regulation of heart growth and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0070848 and response to growth factor and biological process, this GO :0004721: phosphoprotein phosphatase activity, this GO :0004721: phosphoprotein phosphatase activity and also this GO :0004725: protein tyrosine phosphatase activity and also this GO :0005515: protein binding and also this GO :0008138: protein tyrosine/serine/threonine phosphatase activity and also this GO :0016791: phosphatase activity and also this GO :0017017: MAP kinase tyrosine/serine/threonine phosphatase activity, this GO :0004725: protein tyrosine phosphatase activity, this GO :0005515: protein binding, this GO :0008138: protein tyrosine/serine/threonine phosphatase activity, this GO :0016791: phosphatase activity, this GO :0017017: MAP kinase tyrosine/serine/threonine phosphatase activity, dual specificity phosphatase 6
Identity 3072
Gene DUSP6
Long gene name dual specificity phosphatase 6
Synonyms MKP-3 PYST1
Locus 12q21, 33
Discovery year 1997-03-19
GenBank acession BC037236
Entrez gene record 1848
Pubmed identfication 8626780 9205128
RefSeq identity NM_001946 NM_022652
Classification MAP kinase phosphatases
Havana BLAST/BLAT OTTHUMG00000169912

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