Eph receptor A7 Antibody

Eph receptor A7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	Eph receptor A7 Primary Polyclonal Antibody
Also known as	Eph receptor A7 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	EphA7
Specificity	There is a chance that this protein will cross-react with EphA4 based on a 73% non-sequential sequence similarity, This is a highly specific antibody against EphA7
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen range	203-253/998
Subcellular location	Extracellular
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EphA7
Gene ID number	2045
Swiss Prot	Q15375
Tested Applications	FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions	FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion, Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7, May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, leading to contact-dependent bidirectional signaling into neighboring cells, Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	EHK-3, EK11, EPH homology kinase 3, EPH-like kinase 11, EPHA7, Ephrin type-A receptor 7, HEK11, EHK3
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description	2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene target	Eph receptor A7
Short name	Eph receptor A7 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	Eph receptor A7 (Antibody to)
Alternative technique	antibodies
Identity	3390
Gene	EPHA7
Long gene name	EPH receptor A7
Synonyms gene name	EphA7
Synonyms	Hek11
Locus	6q16, 1
Discovery year	1997-10-10
GenBank acession	L36642
Entrez gene record	2045
Pubmed identfication	9267020
Classification	Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors
Havana BLAST/BLAT	OTTHUMG00000015228

Eph receptor A7 Antibody

Eph receptor A7 Antibody size: 0.1ml 263

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