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eRF1 Antibody

eRF1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameeRF1 Primary Polyclonal Antibody
Also known aseRF1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigeneRF1
SpecificityThis is a highly specific antibody against eRF1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human eRF1
Gene ID number2107
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen GTP and the ribosome, In eukaryotes, Termination of protein synthesis takes place when the ribosomal A site is occupied simultaneously by one of three stop codons and by a class 1 translation termination factor, The gene encoding human eRF1 maps to chromosome 5q31, This complex performs a dual role, a protein that promotes hydrolysis of the last peptidyl-tRNA on the ribosome, and, eRF1 activity is stimulated by the association with the GTP-binding protein eRF3, eRF1 contains a highly conserved Asn-Ile-Lys-Ser (NIKS) tetrapeptide, eRF1 forms a quaternary complex with eRF3, elongation and termination, in the â, in the â, this termination factor is the eukaryotic release factor 1 (eRF1), where, which is essential for the interaction of eRF1 with the ribosome, â, â, &euro, &euro, &euro, &euro, &oelig, &oelig, 2, GDP state, GTP state, Translation is carried out by the ribosome and several associated protein factors through three consecutive steps: initiation,  it controls the positioning of eRF1 toward the stop codon and peptidyl-tRNA,  it promotes the release of the eRFs from the ribosome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names D5S1995, ERF, ERF1_HUMAN, ETF1, Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, Eukaryotic translation termination factor 1, MGC111066, Polypeptide chain release factor 1, Protein Cl1, RF1, SUP45L1, Sup45 yeast omnipotent suppressor 45 homolog like 1, TB3 1, TB3-1, eRF1, Cl1 protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targeteRF1
Short nameeRF1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameeRF1 (Antibody to)
Alternative techniqueantibodies
Identity 3477
Gene ETF1
Long gene name eukaryotic translation termination factor 1
Synonyms gene SUP45L1 ERF1 ERF
Synonyms eRF1 TB3-1 RF1
Synonyms name sup45 (yeast omnipotent suppressor 45) homolog-like 1 polypeptide chain release factor 1
Locus 5q31, 2
Discovery year 1991-06-13
GenBank acession AF095901
Entrez gene record 2107
Pubmed identfication 1546371 7990965
RefSeq identity NM_004730
Havana BLAST/BLAT OTTHUMG00000129199

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