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Factor I heavy chain Antibody

Factor I heavy chain Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFactor I heavy chain Primary Polyclonal Antibody
Also known asFactor I heavy chain PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFactor I heavy chain
SpecificityThis is a highly specific antibody against Factor I heavy chain
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Complement factor I heavy chain
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CR1 or MCP are required for C3b cleavage, Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases, Factor H, Factor I is a serine protease with a high degree of specificity for C3b and C4b, It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, It requires protein cofactors for cleavage of these complement proteins, There are three pathways of complement activation: the classical pathway, and C4bp or CR1 are required for C4b cleavage, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis, lectin pathway and alternative pathway, The complement pathway is an important host defense system that contributes to both innate and acquired immunity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names , AHUS3, C3B/C4B inactivator, C3BINA, C3b INA, C3b inactivator, CFAI_HUMAN, CFI, Complement component I, Complement control protein factor I, Complement factor I, Complement factor I heavy chain, F1, FI, FactorI, Heavy chain of factor I, I factor, KAF, Konglutinogen activating factor, OTTHUMP00000219728, factor I, Factor I heavy chain
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFactor I heavy chain
Short nameFactor I heavy chain Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFactor I heavy epitope (Antibody to)
Alternative techniqueantibodies

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