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GAB2 (Ser623) Antibody

GAB2 (Ser623) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGAB2 (Ser623) Primary Polyclonal Antibody
Also known asGAB2 (Ser623) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGAB2 Ser623
SpecificityThis is a highly specific antibody against GAB2 Ser623
Modification(s)Phosphorylation
Modification site(s)Ser623
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human GAB2 around the phosphorylation site of Ser623
Gene ID number9846
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CrkL and SHC, Gab2 acts as a docking protein for several SH2-containing proteins, Gab2 interacts with SHP2 tyrosine phosphatase and GRB2 adaptor protein PI3-kinase, Gab2 is a substrate of various RTKs, Upon tyrosine phosphorylation, cytokine receptors as well as B and T cell antigen receptors, growth factors and cytokines, including EGFR, insulin receptor, Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GAB 2, GAB2_HUMAN, GRB 2 associated binding protein 2, GRB2 associated binder 2 pp100, GRB2 associated binder 2 pp100, GRB2 associated binding protein 2, GRB2-associated binder 2, GRB2-associated-binding protein 2, Gab2, Grb 2 associated binder 2, Grb2 associated binder 2, Growth factor receptor bound protein 2 associated protein 2, Growth factor receptor bound protein 2-associated protein 2, KIAA0571, PH domain containing adaptor molecule p97, p-GAB2 phospho S623, p97, pp100, GAB2 phospho S623
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGAB2 (Ser623)
Short nameGAB2 (Ser623) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGRB2-associated binding protein 2 (Ser623) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target GAB2 and IDBG-65975 and ENSG00000033327 and 9846, Plasma membranes, phosphatidylinositol-3, this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005547 and phosphatidylinositol-3, this GO :0005068: transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005068: transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005070: SH3/SH2 adaptor activity and also this GO :0005515: protein binding and also this GO :0005547: phosphatidylinositol-3, this GO :0005070: SH3/SH2 adaptor activity, this GO :0005515: protein binding, this GO :0005547: phosphatidylinositol-3, this GO :0043325: phosphatidylinositol-3, 4, 4, 4, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0043325: phosphatidylinositol-3, 5-trisphosphate binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043306 and positive regulation of mast cell degranulation and biological process this GO :0043325 and phosphatidylinositol-3, GRB2-associated binding protein 2
Identity 14458
Gene GAB2
Long gene name GRB2 associated binding protein 2
Synonyms KIAA0571
Synonyms name Grb2-associated binder 2
Locus 11q14, 1
Discovery year 2001-01-24
GenBank acession AB011143
Entrez gene record 9846
Pubmed identfication 10391903 10068651
RefSeq identity NM_080491
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000166673

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