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GPR43 Antibody

GPR43 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGPR43 Primary Polyclonal Antibody
Also known asGPR43 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGPR43
SpecificityThis is a highly specific antibody against GPR43
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range63-84/330
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPR43
Gene ID number2867
Swiss ProtO15552
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Finally, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, In addition to SCFAs, In omnivorous mammals, In parallel to its role in energy homeostasis, Its activation results in the formation of inositol 1, May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils, May also regulate the production of LEP/Leptin, May play a role in glucose homeostasis by regulating the secretion of GLP-1, PubMed:12711604, PubMed:23589301), SCFAs serve as a source of energy but also act as signaling molecules, That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, a hormone acting on the central nervous system to inhibit food intake, and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity, in response to short-chain fatty acids accumulating in the intestine, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097), may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers, regulating the rapid production of chemokines and cytokines, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation, the short chain fatty acids (SCFAs), the short chain fatty acids acetate, 4, 5-trisphosphate, G protein-coupled receptor that is activated by a major product of dietary fiber digestion
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FFA2, FFAR2, Free fatty acid receptor 2, G-protein coupled receptor 43, GPCR43, GPR43, FFA2R
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGPR43
Short nameGPR43 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGPR43 (Antibody to)
Alternative techniqueantibodies
Identity 4501
Gene FFAR2
Long gene name free fatty acid receptor 2
Synonyms gene GPR43
Synonyms gene name G protein-coupled receptor 43
Synonyms FFA2R
Locus 19q13, 12
Discovery year 1997-10-10
GenBank acession AF024690
Entrez gene record 2867
Pubmed identfication 9344866
RefSeq identity NM_005306
Classification Free fatty acid receptors
Havana BLAST/BLAT OTTHUMG00000183303

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