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HER4 (Tyr1188) Antibody

HER4 (Tyr1188) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHER4 (Tyr1188) Primary Polyclonal Antibody
Also known asHER4 (Tyr1188) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHER4 Tyr1188
SpecificityThis is a highly specific antibody against HER4 Tyr1188
Modification(s)Phosphorylation
Modification site(s)Tyr1188
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1188
Gene ID number2066
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Alternatively spliced variants which encode different protein isoforms have been described, It encodes a single-pass type I membrane protein with multiple cysteine rich domains, Jul 2008], Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment, Mutations in this gene have been associated with cancer, The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation, [provided by RefSeq, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif, a transmembrane domain, a tyrosine kinase domain, however, not all variants have been fully characterized, This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Avian erythroblastic leukemia viral oncogene homolog 4, Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4, ErbB4, HER 4, HER4, MGC138404, P180erbB4, Receptor protein tyrosine kinase erbB 4 precursor, Receptor tyrosine protein kinase erbB 4, VERBB2, Verba avian erythroblastic leukemia viral oncogene homolog like 4, Verba erythroblastic leukemia viral oncogene homolog 4, p-ErbB 4 phospho Y1188, v erb a avian erythroblastic leukemia viral oncogene homolog like 4, v erb a erythroblastic leukemia viral oncogene homolog 4, ErbB 4 phospho Y1188, Tyrosine kinase type cell surface receptor HER4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHER4 (Tyr1188)
Short nameHER4 (Tyr1188) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHER4 (Tyr1188) (Antibody to)
Alternative techniqueantibodies
Identity 3432
Gene ERBB4
Long gene name erb-b2 receptor tyrosine kinase 4
Synonyms gene name v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Synonyms ALS19 HER4
Synonyms name human epidermal growth factor receptor 4
Locus 2q34
Discovery year 1995-09-07
GenBank acession L07868
Entrez gene record 2066
Pubmed identfication 7700649 17018285
RefSeq identity NM_001042599
Classification Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000133012

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