Filters

HES3 Antibody

HES3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHES3 Primary Polyclonal Antibody
Also known asHES3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHES3
SpecificityThis is a highly specific antibody against HES3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HES3
Gene ID number390992
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen HES1 and HES2 are expressed in a variety of adult and embryonic tissues, HES1-6, HES2 binds to both N and E box sites, HES3 is expressed exclusively in cerebellar Purkinje cells, HES6 inhibits HES1 activity, HES6 is produced in brain as well as in the limb buds of developing embryos, Most HES family members, Rather, The HES family members form a complex with TLE, The HES/TLE complex functions by directly binding to DNA, The mammalian homologues of Drosophila hairy and Enhancer of split are the HES gene family members, and HES5 is found solely in the nervous system, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins, including HES1 and HES5, instead of interfering with activator proteins, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG), the mammalian homologue of Groucho, thereby promoting transcription, which also encode bHLH transcriptional repressors that regulate myogenesis and neurogenesis, while HES6 does not bind DNA, The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Class B basic helix loop helix protein 43, Hairy and enhancer of split 3, Transcription factor HES 3, bHLHb43
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHES3
Short nameHES3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHES3 (Antibody to)
Alternative techniqueantibodies
Identity 26226
Gene HES3
Long gene name hes family bHLH transcription factor 3
Synonyms gene name hairy and enhancer of split 3 (Drosophila)
Synonyms bHLHb43
Locus 1p36, 31
Discovery year 2005-05-17
Entrez gene record 390992
RefSeq identity NM_001024598
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000001271

Similar products

Subscribe to our Newsletter