| Long name | Recombinant Human Proprotein convertase subtilisin/kexin type 9 (PCSK9) |
| Alternative names | NARC-1, Neural apoptosis-regulated convertase 1, PC9, Proprotein convertase 9, Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9, convertase subtilisin/kexin type 9 preproprotein, neural apoptosis regulated convertase 1, proprotein convertase subtilisin/kexin type 9, proprotein convertase subtilisin/kexin type 9, subtilisin/kexin-like protease PC9, proprotein convertase subtilisin/kexin type 9 preproprotein |
| Gene name | PCSK9 |
| Other gene names | FH3, HCHOLA3, LDLCQ1, NARC-1, NARC-1, NARC1, NARC1, PC9, PC9, PCSK9, PCSK9 |
| General description | All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Proprotein convertase subtilisin/kexin type 9(PCSK9) is a recombinant protein expressed in Baculovirus |
| Product category | Recombinant Proteins |
| Expression system | Baculovirus |
| Available also expressed in: | Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity | Greater than 90% (determined by SDS-PAGE) |
| Form | Lyophilized protein |
| Storage | Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications | IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target | Proprotein convertase subtilisin/kexin 9 (PCSK9) |
| Short name | Proprotein convertase subtilisin/kexin type 9 (PCSK9) |
| Species | Humans, Human |
| Alternative name | sapiens Proprotein convertase subtilisin/kexin classification 9 (proprotein convertase subtilisin/kexin classification 9), H |
| Alternative to gene target | Extracellular, PCSK9 and IDBG-99082 and ENSG00000169174 and 255738, Pcsk9 and IDBG-170186 and ENSMUSG00000044254 and 100102, this GO :0001822 and kidney development and biological process this GO :0001889 and liver development and biological process this GO :0001920 and negative regulation of receptor recycling and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005791 and rough endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007041 and lysosomal transport and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0009986 and cell surface and cellular component this GO :0010469 and regulation of receptor activity and biological process this GO :0010989 and negative regulation of low-density lipoprotein particle clearance and biological process this GO :0016485 and protein processing and biological process this GO :0016540 and protein autoprocessing and biological process this GO :0019871 and sodium channel inhibitor activity and molecular function this GO :0022008 and neurogenesis and biological process this GO :0030134 and ER to this GO lgi transport vesicle and cellular component this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030182 and neuron differentiation and biological process this GO :0031232 and extrinsic component of external side of plasma membrane and cellular component this GO :0032799 and low-density lipoprotein receptor particle metabolic process and biological process this GO :0032802 and low-density lipoprotein particle receptor catabolic process and biological process this GO :0032803 and regulation of low-density lipoprotein particle receptor catabolic process and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0034189 and very-low-density lipoprotein particle binding and molecular function this GO :0034190 and apolipoprotein receptor binding and molecular function this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0043621 and protein self-association and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050750 and low-density lipoprotein particle receptor binding and molecular function this GO :0070326 and very-low-density lipoprotein particle receptor binding and molecular function, this GO :0004252: serine-type endopeptidase activity, this GO :0004252: serine-type endopeptidase activity and also this GO :0005515: protein binding and also this GO :0019871: sodium channel inhibitor activity and also this GO :0030169: low-density lipoprotein particle binding and also this GO :0034185: apolipoprotein binding and also this GO :0034189: very-low-density lipoprotein particle binding and also this GO :0034190: apolipoprotein receptor binding and also this GO :0043621: protein self-association and also this GO :0044822: poly(A) RNA binding and also this GO :0050750: low-density lipoprotein particle receptor binding and also this GO :0070326: very-low-density lipoprotein particle receptor binding, this GO :0005515: protein binding, this GO :0019871: sodium channel inhibitor activity, this GO :0030169: low-density lipoprotein particle binding, this GO :0034185: apolipoprotein binding, this GO :0034189: very-low-density lipoprotein particle binding, this GO :0034190: apolipoprotein receptor binding, this GO :0043621: protein self-association, this GO :0044822: poly(A) RNA binding, this GO :0050750: low-density lipoprotein particle receptor binding, this GO :0070326: very-low-density lipoprotein particle receptor binding, very-low-density lipoprotein particle receptor binding, proprotein convertase subtilisin/kexin type 9 |
| Identity | 20001 |
| Gene | PCSK9 |
| Long gene name | proprotein convertase subtilisin/kexin type 9 |
| Synonyms gene | HCHOLA3 |
| Synonyms gene name | autosomal dominant 3 , hypercholesterolemia |
| Synonyms | NARC-1 FH3 |
| Locus | 1p32, 3 |
| Discovery year | 2003-05-13 |
| GenBank acession | AX207686 |
| Entrez gene record | 255738 |
| Pubmed identfication | 12552133 12730697 |
| RefSeq identity | NM_174936 |
| Classification | Proprotein convertase subtilisin/kexin family |
| Havana BLAST/BLAT | OTTHUMG00000008136 |
| Locus Specific Databases | British Heart Foundation LRG_275 |
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