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KLF1, 2, 4 Antibody

KLF1, 2, 4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name 2, 4 Primary Polyclonal Antibody, KLF1
Also known as 2, 4 PAb, KLF1
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigen 2, 4, KLF1
Specificity 2, 4, This is a highly specific antibody against KLF1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range279-303/362
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLF1
Gene ID number10661
Swiss ProtQ13351
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Able to activate CD44 and AQP1 promoters, Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene, Furthermore, Is a dual regulator of fetal-to-adult globin switching, This dual activity ensures that, When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation (By similarity), fetal hemoglobin levels are low, in most adults, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes, Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDAN4, Erythroid krueppel-like transcription factor, HBFQTL6, INLU, KLF1, Krueppel-like factor 1, EKLF
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target 2, 4, KLF1
Short name 2, 4 Antibody, KLF1
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name 2, 4 (Antibody to), Kruppel-like factor 1 (erythroid)
Alternative techniqueantibodies
Alternative to gene target CDAN4 and EKLF and HBFQTL6 and INLU, DNA-templated and biological process this GO :0030218 and erythrocyte differentiation and biological process this GO :0035162 and embryonic hemopoiesis and biological process this GO :0043249 and erythrocyte maturation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048821 and erythrocyte development and biological process this GO :1901653 and cellular response to peptide and biological process, KLF1 and IDBG-31252 and ENSG00000105610 and 10661, KLF1 and IDBG-642908 and ENSBTAG00000006083 and 784295, Klf1 and IDBG-175231 and ENSMUSG00000054191 and 16596, metal ion binding, nuclei, this GO :0000790 and nuclear chromatin and cellular component this GO :0000987 and core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0001889 and liver development and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, this GO :0000987: core promoter proximal region sequence-specific DNA binding, this GO :0000987: core promoter proximal region sequence-specific DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046872: metal ion binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0044212: transcription regulatory region DNA binding, this GO :0046872: metal ion binding, Kruppel-like factor 1 (erythroid)
Identity 6345
Gene KLF1
Long gene name Kruppel like factor 1
Synonyms gene name Kruppel-like factor 1 (erythroid)
Synonyms EKLF
Synonyms name erythroid Kruppel-like factor
Locus 19p13, 13
Discovery year 1999-12-14
GenBank acession U37106
Entrez gene record 10661
Pubmed identfication 8924208 9119377
RefSeq identity NM_006563
Classification Kruppel like factors Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000180536
Locus Specific Databases LRG_825

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